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AP Biology Quiz for Chapter 17


1. What is the relationship among DNA, a gene, and a chromosome?
a. A chromosome contains hundreds of genes which are composed of protein.
b. A chromosome contains hundreds of genes which are composed of DNA.
c. A gene contains hundreds of chromosomes which are composed of protein.
d. A gene is composed of DNA, but there is no relationship to a chromosome.
e. A gene contains hundreds of chromosomes which are composed of DNA.

2. What is one function of a signal sequence?
a. to direct an mRNA molecule into the cisternal space of ER
b. to bind RNA polymerase to DNA and initiate transcription
c. to terminate translation of the messenger RNA
d. to attach ribosomes synthesizing secretory proteins to the ER
e. to signal the initiation of transcription

3. Which of the following is FALSE?
a. Transcriptionally produced gene products are molecules of RNA.
b. Proteins are translated in the cytoplasm.
c. Steroid hormones may bind directly to DNA and regulate expression.
d. Histones are found only in eukaryotic chromosomes.
e. RNA polymerase attaches to DNA at the promoter sequence.

4. Which of the following is true for both prokaryotic and eukaryotic gene expression?
a. After transcription, a 3' poly A tail and a 5' cap are added to mRNA.
b. Translation of mRNA can begin before transcription is complete.
c. RNA polymerase may recognize a promoter region upstream from the gene.
d. mRNA is synthesized in the 3' --> 5' direction.
e. The mRNA transcript is the exact complement of the gene from which it was copied.

5. A particular triplet of bases in the coding sequence of DNA is AGT. What is the corresponding triplet in the complementary strand of DNA?
a. AGT
b. UCA
c. TCA
d. GAC
e. TCA in eukaryotes, but UCA in prokaryotes.

6. The corresponding codon for the mRNA transcribed from the gene is:
a. AGT
b. UCA
c. TCA
d. AGU
e. Either UCA or TCA, depending on wobble in the first base.

7. The anticodon on the tRNA that binds this mRNA codon is:
a. AGT
b. UCA
c. TCA
d. AGU
e. Either UCA or TCA, depending on wobble in the first base.

8. RNA differs from DNA in that RNA
  1. contains ribose as its sugar.
  2. is found only in cytoplasm.
  3. contains uracil instead of thymine.

a. 1
b. 2
c. 3
d. 1 and 3 are correct.
e. 1, 2, and 3 are correct.

9. When a ribosome first attaches to an mRNA molecule, one tRNA binds to the ribosome. The tRNA that recognizes the initiation codon binds to the
  1. amino acid site (A site) of the ribosome only.
  2. peptide site (P site) of the ribosome only.
  3. large ribosomal subunit only.
  4. second tRNA before attaching to the ribosome.

a. 1
b. 2
c. 3
d. 4
e. Both 1 and 3 are correct.


----------------------------------------------------- Refer to Figure 16.1 to answer the following question(s).
Figure 16.1
10. What amino acid sequence will be generated, based on the following mRNA codon sequence? 5'-AUG-UCU-UCG-UUA-UCC-UUG
a. met-arg-glu-arg-glu-agr
b. met-glu-arg-arg-gln-leu
c. met-ser-leu-ser-leu-ser
d. met-ser-ser-leu-ser-leu
e. met-leu-phe-arg-glu-glu

11. The first event in translation of eukaryotes (starting with methionine) is the
a. joining of the ribosomal subunits.
b. base pairing of met-tRNA to AUG of the messenger RNA.
c. binding of the large ribosomal subunit to AUG of mRNA.
d. covalent bonding between the first two amino acids.
e. forming of polysomes.

12. All of the following are transcribed from DNA EXCEPT
a. protein.
b. exons.
c. rRNA.
d. tRNA.
e. mRNA.

13. Where is ribosomal RNA transcribed?
a. the Golgi apparatus
b. ribosomes
c. nucleoli
d. X chromosomes
e. prokaryotic cells only

14. Which of the following does not occur during the termination phase of translation?
a. A termination codon moves into the A site.
b. The newly formed polypeptide is released.
c. A tRNA with the next amino acid enters the P site.
d. The two ribosomal subunits separate.
e. Translation stops.

15. Beadle and Tatum proposed the one gene-one enzyme concept. In its original form, this hypothesis could be restated in which of the following ways?
a. One DNA molecule contains the information to make one enzyme.
b. A given sequence of DNA nucleotides contains the information to make one enzyme.
c. Each gene contains the information to make one enzyme, one lipid, and one carbohydrate.
d. Each gene is actually an enzyme that catalyzes the production of one protein.
e. Each polypeptide is the result of the activity of one enzyme.